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. Author manuscript; available in PMC: 2020 Apr 1.

Published in final edited form as: Ocul Surf. 2019 Jan 8;17(2):221–229. doi: 10.1016/j.jtos.2019.01.003

Table 3.

Comparisons on the outcome between AM and fibrin as the substrate in CLET and COMET

substrate	AM	Fibrin
*Reepithelization time (Day)*
CLET	5-13.7 ^138,144
COMET	5.2 ¹²⁷
*Successful rate*
CLET
1Y	60%-91% ^{29,93,113,118-120,136,138,142-144}	62%-80% ^102,103,158
2Y	56%-81% ^{32,110,114,117-120,135-138,140,141}
3Y	47%-75% ^{119,120,134,136,138}	77% ⁹⁹
4Y	45% ¹¹⁸
5Y	64%-75% ^136,139
8Y		66% ¹⁵⁹
COMET
1Y		63%-88% (substrate free)^146,147
	44%-65% ^{123,127,129,147}
2Y	59%-79% ^127,129	64% (fibrin) ¹⁶⁰
3Y	53%-71% ^126,129,145

AM: amniotic membrane; CLET: cultivated limbal epithelial transplantation; COMET: cultivated oral mucosal epithelial transplantation;