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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Ocul Surf. 2018 Dec 4;17(2):310–317. doi: 10.1016/j.jtos.2018.12.001

Figure 5.

Figure 5.

Effects of low O2 on IHMGEC proliferation and differentiation. Low O2 treatment did not impact the cell growth (A) or the expression of PCNA (B). SREBP-1, but not Lamp-1, expression is significantly increased in a hypoxic environment (C and D, † p < 0.05, n = 3 experiments). AZM with or without low O2 significantly increased the levels of Lamp-1 protein. (E, * p < 0.05, ** p< 0.01, n=3 experiments). DM = Differentiation Medium (DMEM/F12 + 10% FBS). PM = Proliferation Medium (KSFM + EGF/BPE).