Figure 4. SNV mutation spectrums in the seven environments.
Mutation spectrum variation among the seven environments is significant in each panel (P < 10−3, chi-squared test). Differences in mutation spectrum, Ts/Tv ratio, or GC-to-AT/AT-to-GC ratio between a medium and YPD is assessed by a chi-squared test followed by Bonferroni correction for multiple testing (*, P < 0.05; **, P < 0.01; ***, P < 0.001). In all panels, the six non-YPD environments are ordered from high to low growth rates on the X-axis.
(A) Proportions of the six types of single nucleotide variation.
(B) The transition/transversion ratio (Ts/Tv).
(C) The ratio of the number of GC-to-AT mutations to that of AT-to-GC mutations.