Table I.

List of CD82 SNPs associated with cytokine changes and candidemia susceptibility

SNPs	eQTL p-value	Cytokine Affected	Affected Sample	cQTL p-value	Candidemia Susceptibility p-value	Risk Allele Frequency	Candidemia Susceptibility Odds Ratio
rs12282890	6.22E-06	IL-1β	Candida blastospores, (HK), WB, 48 hr	0.0122	NS	n/a	n/a
rs12282890	6.22E-06	IL-17	C. albicans blastospores, PBMC, 7 days	0.0471	NS	n/a	n/a
rs1429553	1.11E-03	IL-6	C. albicans hyphae, PBMC, 24 hr	0.0018	NS	n/a	n/a
rs7932712	0.0014	none	n/a	NS	0.0215	C, 0.71	1.49

List of CD82 SNPs in the 500 FG cohort for Candida-induced cytokines and candidemia susceptibility in whole blood (WB) or peripheral blood mononuclear cell (PBMC) samples. Two polymorphisms were associated with changes to IL-1β, IL-17, and IL-6 cytokines. The SNP rs7932712 was associated with an elevated susceptibility to develop candidemia. eQTL, SNPs correlated with expression level of CD82; cQTL, SNPs correlated with cytokine levels; NS, SNPs were tested but are not associated with the phenotype.