Table 1.
Parameters | Body weight (g) | Lung (mg) (%) | Thymus (mg) (%) | Spleen (mg) (%) | Kidneys (mg) (%) | Liver (mg) (%) | |
---|---|---|---|---|---|---|---|
DZF | VHF | 25.40 ± 1.68 | 189.38 ± 6.63 | 54.50 ± 5.68 | 72.50 ± 5.31 | 339.25 ± 7.95 | 945.63 ± 42.58 |
0.76 ± 0.04 | 0.22 ± 0.02 | 0.29 ± 0.01 | 1.36 ± 0.06 | 3.77 ± 0.14 | |||
2 mg/kg | 29.79 ± 1.41 | 204.50 ± 7.71 | 64.00 ± 4.77 | 69.13 ± 3.72 | 358.25 ± 14.33 | 1045.88 ± 58.81 | |
0.69 ± 0.02 | 0.21 ± 0.01 | 0.23 ± 0.00** | 1.21 ± 0.04 | 3.51 ± 0.08 | |||
6 mg/kg | 30.87 ± 1.50 | 203.75 ± 10.74 | 64.00 ± 4.91 | 66.63 ± 1.76 | 356.13 ± 13.24 | 999.38 ± 45.36 | |
0.66 ± 0.03 | 0.21 ± 0.01 | 0.22 ± 0.01** | 1.16 ± 0.02* | 3.25 ± 0.09** | |||
20 mg/kg | 31.34 ± 3.06 | 174.75 ± 8.47 | 69.38 ± 4.57 | 67.25 ± 4.53 | 376.13 ± 16.09 | 1002.88 ± 75.92 | |
0.58 ± 0.05** | 0.23 ± 0.01 | 0.22 ± 0.01** | 1.25 ± 0.07 | 3.25 ± 0.09** |
Mice were maintained on a soy-based diet and administered vehicle (25 mM Na2CO3 or daidzein by gavage daily for 14 days. At study termination, the mice were necropsied and indicated organs weighed. VHF = females exposed to vehicle; DZF = females exposed to daidzein. Values represent the mean ± SE (N = 8).
p ≤ 0.05
p ≤ 0.01