Table 2.

The splenic subpopulations following daidzein exposure in adult B6C3F1 females.

Spleen		NK (%)	IgM+ (%)	CD3+(%)	Neutrophils (%)	CD4+CD25+ (%)	CD4−CD8+ (%)	CD4+CD8− (%)
DZF	VHF	1.98 ±0.48	38.28 ±4.19	16.51 ±2.68	2.16 ±0.36	3.17 ±0.54	4.04 ± 0.65	9.85 ± 1.20
	2 mg/kg	1.74 ±0.20	34.99 ± 1.80	21.53 ± 2.12	1.66 ±0.40	2.58 ±0.67	4.39 ± 0.44	10.15 ± 1.08
	6 mg/kg	2.03 ±0.25	34.28 ±2.50	21.70 ±4.13	1.90 ±0.37	3.28 ± 0.68	6.83 ± 1.07*	14.14 ± 1.89
	20 mg/kg	2.46 ± 0.09	29.12 ± 1.41*	35.00 ± 2.57**	1.12 ±0.08*	2.18 ± 0.12	9.42 ± 0.50**	15.58 ± 1.82*

Mice were maintained on a soy-based diet and administered vehicle (25 mM Na₂CO₃) or daidzein by gavage daily for 14 days, and the percentages of splenocyte subsets were determined using flow cytometric analysis. VHF = females exposed to vehicle; DZF = females exposed to daidzein. Values represent the mean ± SE (N = 8).

^*p ≤ 0.05

^**p ≤ 0.01