Figure 2.

Overview of complete-airway CFD simulations beginning with the site of aerosol formation and continuing through particle deposition. Using the stochastic individual pathway (SIP) approach [13, 28, 55], an ensemble of airway paths is selected within each lung lobe. Only one SIP unit is illustrated in the left lower lobe in this figure. The model of the alveolar region is composed of a representative acinar segment beginning with a respiratory bronchiole and continuing through the alveolar sacs [56]. Complete-airway simulations can be continued through post-deposition transport [14].

Portions redrawn and adapted from Longest and Hindle [14] with permission of Springer Nature.

B#: bifurcation number; LL: left lower; NMT: nose-mouth-throat airway