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. 2019 Apr 25;33(6):7694–7706. doi: 10.1096/fj.201802580R

Figure 5.

Figure 5

Pericyte transplantation improves skeletal muscle capillarization following IM. A) Representative cross section images of capillaries (CD31), collagen type 1, and immune cells (CD11b+). Merged images at original magnification value of ×20. B) C/F ratio is significantly reduced in the stapled muscle of the hydrogel control group. Pericyte transplantation leads to a recovery of the C/F ratio. C) The paired limb difference between Hydrogel and Pericyte groups are significantly different. D) Capillary density is significantly increased in the immobilized TA with pericyte transplantation. E) The paired limb difference demonstrates a significant increase in capillary density in the pericyte group. F, G) Collagen type I content is not altered by RE or pericyte transplantation. B, D, F) Connected circles represent the immobilized and contralateral limbs from an individual sample. *P < 0.05, difference between Stapled and Mobile (with paired t test). Data are means ± sem (n = 5–6). #P < 0.05, paired difference between Hydrogel and Pericyte (with independent samples t test).