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. 2019 Mar 11;46(3):211–222. doi: 10.1007/s10928-018-9614-9

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© Pfizer 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — a Linear clearance^a or b Volume of distribution^b in central compartment versus baseline body surface area by patient type and those receiving rituximab. The red dotted lines are the locally weighted scatterplot smoothing trend line (LOESS). ^a3 outliers of CL₁ > 0.4 L/h were omitted from the plot for better visualization. ^b1 outlier of V₁ > 30 L was omitted from the plot for better visualization