Fig. 4. Neural responses associated with psychophysiological reinstatement effects.

a Differential BOLD responses in the vmPFC during reinstatement test were inversely correlated with Pavlovian reinstatement intensity, indexed by differential SCRs (MNI peak at [x: −6, y: 42, z: −8], p_{FWE ROI} = .022). b Differential SCRs were further marginally inversely correlated with functional amygdala-vmPFC connectivity (gPPI) observed in the second test phase (MNI peak at [x: 6, y: 40, z: −16], p_{FWE ROI} = .061). Overlayed in cyan is the unilateral anatomical ROI mask of the left amygdala used to extract the time course of the seed region for the gPPI analysis. All t-maps are displayed on a visualization threshold of p < .005 uc with k ≥ 20 cluster extend