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. 2019 May 21;9(6):51. doi: 10.1038/s41408-019-0211-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Comet Assay: percent tail DNA measured in HL60 cells transfected with ABCB1 expression constructs in response to calicheamicin treatment. Histograms represented fluoresce microscopy data were analyzed by Image J software to calculate average of tails per each group (***p < 0.001). b Calicheamicin reduced cell viability in HL-60 cells expressing ABCB1-1045642T as compared to ABCB1-WT as determined by AOPI. Dual-fluorescence viability, Acridine orange (AO) and propidium iodide (PI) (*p < 0.05)