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. 2019 May 21;10(6):398. doi: 10.1038/s41419-019-1628-8

Fig. 4. Perifosine regulates RAD51 ubiquitination by inhibiting UCHL3.

Fig. 4

a Control and UCHL3 knockout MDA-MB-231 cells were treated with perifosine and lysates were used for immunoprecipitation and western blot as indicated. b Examination of Rad51 ubiquitination in cells treated with perifosine. c In vitro deubiquitination analysis of UCHL3 in the presence or absence of perifosine