Table 1.

V. parvula genes in key metabolic pathways that were differentially expressed in coaggregates compare with monocultures.

Gene (HSIVP1)	Vpar ID	Gene description	Fold-changea	P adj
Alanine, aspartate and glutamate metabolism
RS00110	Vpar_0075	aspartate aminotransferase	−23	5.5 × 10−3
RS01170	Vpar_0278	L-asparaginase	−21	1.8 × 10−7
RS01260	Vpar_0296	aspartate racemase	−9.5	2.8 × 10−4
RS02565	Vpar_0563	aspartate carbamoyltransferase (pyrB)	−3.8	2.8 × 10−4
RS07610	Vpar_1550	glutamate dehydrogenase	−53	1.0 × 10−5
RS07685	Vpar_1568	argininosuccinate synthase	−11	1.3 × 10−7
Arginine and proline metabolism
RS00110	Vpar_0075	aspartate aminotransferase	−23	5.5 × 10−3
RS01940	Vpar_0438	s-adenosylmethionine decarboxylase proenzyme	−18	4.9 × 10−8
RS06910	Vpar_1429	pyrroline-5-carboxylate reductase (proC)	−4.6	6.1 × 10−3
RS07610	Vpar_1550	glutamate dehydrogenase	−53	1.0 × 10−5
RS07685	Vpar_1568	argininosuccinate synthase	−11	1.3 × 10−7
Mismatch repair
RS08370	Vpar_0002	DNA polymerase III	5.1	0.015
RS04315	Vpar_0919	exodeoxyribonuclease small subunit (xseA)	−7.8	2.5 × 10−2
RS04495	Vpar_0958	DNA polymerase III subunit alpha (polC)	3.8	4.7 × 10−3
RS05520	Vpar_1000	DNA helicase	2.8	4.2 × 10−2
RS05790	Vpar_1213	single-stranded DNA-specific exonuclease	3.1	1.8 × 10−2
Taurine and hypotaurine metabolism
RS05910	Vpar_1231	acetate kinase (ackA)	−2.7	4.2 × 10−2
RS08975	Vpar_1716	phosphate acetyltransferase	−5.7	2.2 × 10−3

^aFold-change in coaggregates versus monocultures.