Skip to main content
. 2019 May 15;10:438. doi: 10.3389/fgene.2019.00438

Table 1.

RHOA involvement in actions of specific chemotherapeutics, and their descriptions.

Compounds Description
Cisplatin (Wang et al., 2015), docetaxel (Wang et al., 2015), 5-fluorouracil (Korourian et al., 2017b), vincristine (Kang et al., 2005), taxol(Kang et al., 2005) Non-coding RNA (miR-29, and -31) epigenetics, involved in chemotherapy efficacy, through RHOA signaling
5-fluorouracil, cisplatin (Yoon et al., 2016) CD44(+) GC CSC cell numbers were decreased by cisplatin combined with RHOA signaling inhibitors; A cancer hallmark term, resisting cell death (cancer stem-like cells, CSCs) associated.

Regarding RHOA, therapeutic agents, and their description are summarized in the table.