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. 2019 May 21;9:7660. doi: 10.1038/s41598-019-44141-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Locomotor recovery quantification. (A) The height of iliac crest defined as the vertical distance between the iliac crest and the runway. Both groups showed a reduced height of iliac crest after the SCI, compared to the healthy animals. Height of iliac crest was significantly increased in laser-treated animals 5 and 9 weeks after the SCI. (B) Maximal negative excursion (retraction) of hindlimb was not changed after the SCI. (C) Maximal positive excursion (protraction) was significantly decreased in all groups after SCI compared to healthy animals before operation. Laser-treated group showed significant improvement of protraction in both time points. (D) Significant decrease of the range of movement in control group compared to laser group. (E) Significant decrease of angle range in knee angle in both groups in both time points compared to healthy animals before operation (p < 0.001). No significant difference between laser and control group. (F) Increase of range in ankle angle in laser treated group compared to healthy animals before operation and control group in both time points. The values are expressed as mean ± SEM. n = 5 per group (3 video records of each animal), *p < 0.05, **p < 0.01, ***p < 0.001. BO – before operation, w – weeks after SCI.