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. 2019 May 21;9:7666. doi: 10.1038/s41598-019-43948-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Expression patterns of Runx1 and Bapx1 in articular cartilage. (a) Immunohistochemistry with antibodies to Bapx1 and β-gal in articular cartilage of Runx1 heterozygous lacZ knock-in mice (Runx^lz/+) under physiological conditions. Scale bars, 100 μm for low and high magnification images. (b) Immunofluorescence with antibodies to GFP and Bapx1 in knee joints of Runx1-IRES-GFP mice under physiological condition. Scale bar, 50 μm. MFC, medial femoral condyle; MTP, medial tibial plateau; MM, medial meniscus.