Table 1.

Multiple linear regression analysis of the association of the change in OSDI score with baseline clinical conditions.

Variable (Baseline value)	Unstandardized coefficient (B)	Standardized coefficient (β)	P value
Meibum expressibility	−18.2	−0.396	0.003
TBUT	4.5	0.453	0.007
Sex (female)	−19.1	−0.396	0.019

The change in the OSDI score is defined as the OSDI after the 3rd treatment session – the OSDI at baseline. Age (P = 0.950), meibum quality (P = 0.980), lid margin abnormality (P = 0.928), and ocular surface staining (P = 0.767) were excluded from the model by using the stepwise method.

P value for the overall model is 0.002 and adjusted R² is 0.368.

OSDI = Ocular Surface Disease Index; TBUT = tear film break-up time.