Table 1.

Protein effectors from Trichoderma functionally validated during the interaction with plants.

Family	Protein	Trichoderma strain	Function in interaction with plants	References
Cerato-platanins	Sm1 (small protein 1)	T. virens	Induction of defense-related genes, production of ROS and phenolic compounds.	Djonovic et al., 2006, Djonovic et al., 2007; Salas-Marina et al., 2015
	Sm2 (small protein 2)	T. virens	Involved in root colonization and plant protection.	Crutcher et al., 2015
	Epl1 (eliciting plant response-like)	T. atroviride	Induction of defense-related genes.	Salas-Marina et al., 2015
		T. harzianum	Induction of defense-related genes.	Gomes et al., 2015
		T. formosa	Triggered of plant immune system.	Cheng et al., 2018
		T. asperellum	Induction of defense-related genes.	Yu et al., 2018
	Swollenin (expansin-like protein)	T. asperellum	Involved in root colonization and induction of plant defense.	Brotman et al., 2008
Glycoside-hydrolases	Thph1 and Thph2 (cellulase-like protein)	T. harzianum	Induction of defense-related genes.	Saravanakumar et al., 2016
	Cellulases	T. longibrachiatum	Activation of plant defense pathways.	Martínez et al., 2001
	ThPG1	T. harzianum	Involved on colonization of plant roots.	Morán-Diez et al., 2009
	Eix (xylanase)	T. viride	Triggers ET biosynthesis and hypersensitive response.	Rotblat et al., 2002
Hydrophobins	HYTLO1	T. longibrachiatum	Activate defense-related responses and growth promotion.	Ruocco et al., 2015; Moscatiello et al., 2018
	TVHYDII1	T. virens	Involved in colonization of plant roots.	Guzmán-Guzmán et al., 2017
	HBF2-6	T. asperellum	Involved in root colonization and induction of JA and SA pathways.	Huang et al., 2015
	TasHyd1	T. asperellum	Involved in root colonization.	Viterbo and Chet, 2010

The effectors are divided by families, we indicate the strain from Trichoderma that produce the protein effector and their function in plants.