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. 2019 May 15;10:1077. doi: 10.3389/fimmu.2019.01077

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Copyright © 2019 Butler, Sinkora, Wang, Stepanova, Li and Cai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PRRSV-induced hypergammaglobulinemia in isolator piglets. Serum IgG, IgA, and IgM levels during 4 weeks post infection in isolator piglets infected with low pathogenic PRRSV strain VR-2332, PCV-2, SIV, and germfree controls. Also shown are levels in PRRSV-infected isolator piglets that were colonized with benign E. coli. Double arrows indicate the mean Ig levels at 28 days postpartum in conventionally-reared piglets. Error bars are SEM. Those for PCV-2 and SIV are often smaller than the symbol and were therefore omitted. Legend is on the figure.