Table 2.
Per-patient sensitivity and specificity for metastatic disease
| Patients with metastatic disease* |
Sensitivity |
Patients without metastatic disease* |
Specificity |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| WB-MRI staging pathway† | Standard staging pathway | Difference | p value | WB-MRI staging pathway† | Standard staging pathway | Difference | p value | |||
| Diagnostic accuracy | 52 | 50% (37 to 63) | 54% (41 to 67) | −4% (−15 to 7) | p=0·73 | 135 | 93% (88 to 96) | 95% (91 to 98) | −2% (−7 to 2) | p=0·45 |
| Equivocal lesions considered negative | 52 | 48% (35 to 61) | 46% (33 to 59) | 2% (−11 to 14) | .. | 135 | 94% (89 to 97) | 97% (93 to 99) | −3% (−6 to 1) | .. |
Data are n or % (95% CI).
Patients by consensus reference standard.
WB-MRI plus additional generated tests.