Figure 3.

Survival of patients with idiopathic pulmonary fibrosis patients up to 5 years after diagnosis

Data are stratified by absolute monocyte count ≥0·95 K/μL or <0·95 K/μL. With lung transplantation as a censoring event and after adjusting for age and sex, monocyte count ≥0·95 K/μL was significantly associated with increased risk of mortality in the Stanford (A), Vanderbilt (B), and Optum cohorts (C). Hazard ratios (HRs) for monocyte counts and outcomes across the COMET, Stanford, and Northwestern systemic sclerosis with interstitial lung disease (SSc-ILD) cohorts, adjusted for forced vital capacity (FVC) and gender, age, and physiology (GAP) index (D). Bold text shows the combined HRs for poor outcomes across the three cohorts. There was no heterogeneity in FVC-adjusted and GAP-adjusted HRs across the three cohorts.