Table 2.

Relation between patient’s characteristics with ccfDNA (ALU115) and integrity (ALU247/ALU115) in increased prostate volume and normal prostate volume group

	Number of patients	ccfDNA (ALU115) Median(range) (ng/μL)	P-value	P-value	Integrity (ALU247/ALU115)	P-value	P-value
PCa							0.001
Prostate volume
<35 g (25 cc)	5	49.09	0.956		0.33	0.368
35g (25 cc)–50g (70 cc)	13	50.59			0.34
≫50 g (70 cc)	12	57.12			0.37
BPH
Prostate volume
<35 g (25 cc)	6	12.15	0.161	0.207	0.14	0.363
35 g (25 cc)–50 g (70 cc)	20	13.06			0.16
≫50 g (70 cc)	14	15.60			0.17
Healthy subject
Prostate volume
<35 g (25 cc)	27	–	–		–	–
35 g (25 cc)–50 g (70 cc)	3
≫50 g (70 cc)	0

Abbreviations: PCa, prostate cancer; BPH, benign prostate hypertrophy; ccfDNA, circulation cell-free DNA.