TABLE 2.
MIC of RIF for M. smegmatis wild-type, ΔsigB, and ΔsigB strains overexpressing either M. smegmatis sigB or sigAa
| Strain | MIC of RIF (μg/ml) |
|---|---|
| WT mc2155 | 10 |
| mc2155 ΔsigB | 2.5 |
| mc2155 ΔsigB sigBOE | >10 |
| mc2155 ΔsigB sigAOE | >10 |
a
The survival of M. smegmatis wild-type strain mc2155, mc2155 ΔsigB, and mc2155 ΔsigB overexpressing M. smegmatis sigB and sigA (mc2155 ΔsigB sigBOE and mc2155 ΔsigB sigAOE, respectively) was determined in a 2-fold dilution series of RIF in Middlebrook 7H9 medium. The minimum concentration of antibiotic required to inhibit 99% of the growth is shown.