FIG 5.

Phylogenetic tree showing surface divergence between pilins from each major clade. An alignment of both experimentally solved and modeled structures reveals that pilins from each clade present extremely diverse surfaces to the immune system. The surface of each pilin was compared with that of T18.1, with residues identical to those of T18.1 shown in green and residues that differ from those of T18.1 shown in blue. The pilin lysine is in red. Each pilin is viewed at 0° and 90° rotations around the y axis.