Architectures of effectors containing the PI4P-M-binding domain and the three predicted PI-binding LEDs. Each protein architecture containing the PI4P-M-binding domain, LED006, LED027, or LED035 is represented by a single effector. Several known domains, as well as unknown LEDs, were found in the same architecture with two or three of the domains known or predicted to bind PIs (see summary in Fig. S1). The novel LEDs were originally described elsewhere (35). For each of the analyzed C-terminal domains, the upper effector represents a large group of effectors containing the domain with no other known domain or LED. The effectors presented are indicated on the right by their locus tag or gene name.