Table 4.
Summarised themes for responses to open-ended questions.
N (%) | |
---|---|
Participants' general opinions towards placebo surgery in clinical trials | |
Do not see any value/benefit in placebo surgery | 15 (27.8) |
Have concerns about placebo surgery (e.g. ethical, costs) | 11 (20.4) |
Have not formed an opinion yet (e.g. due to lack of information) | 12 (22.2) |
Understand the importance and benefits of placebo surgery | 12 (22.2) |
Other | 4 (7.4) |
Reasons participants gave for responding no or maybe to participation in a randomised placebo-controlled surgical trial | |
Have concerns about the risks and benefits of placebo surgery | 12 (27.9) |
Have a lack of information or understanding about placebo surgery | 2 (4.7) |
Have unmodifiable personal reasons against placebo surgery | 7 (16.3) |
Have a clear preference for treatment | 6 (13.6) |
Have financial and/or ethical concerns on the cost of the surgery | 5 (11.6) |
Understand the importance of placebo surgery in clinical trials and/or want to contribute to research | 3 (7.0) |
Other (disagree with any kind of surgery or answers not interpretable) | 8 (18.6) |
Factors that would increase willingness to participate in a placebo-controlled trial | |
More information about procedure and/or study | 6 (14.6) |
Certainty and reassurance of good outcome | 8 (19.5) |
Free choice of which treatment received | 5 (12.2) |
Pain levels or functional status | 2 (4.9) |
Advantages to participation | 4 (9.8) |
Support of clinical evidence | 1 (2.4) |
Nothing/unlikely to improve willingness | 11 (26.8) |
Other | 4 (9.8) |
Reasons participants gave against waiting 6 months for surgery (if allocated to placebo group) | |
Do not see the value of randomised trials or only want surgery | 9 (22.5%) |
Need reassurance about positive outcomes after placebo surgery | 5 (12.5%) |
Level of pain and functional status | 9 (22.5%) |
Require immediate treatment due to personal reasons (e.g. age, work) | 11 (27.5%) |
Require more information | 1 (2.5%) |
Other | 5 (12.5%) |