Table 3.

Predictive factors for pathologic complete response using logistic regression analysis

Variable	Univariate analysis			Multivariate analysis
	OR	95% CI	P-value	OR	95% CI	P-value
Age	0.984	0.946–1.023	0.418
Male sex	0.950	0.401–2.248	0.907
RB location	1.130	0.349–3.660	0.838
cT4	0.000	0.000–∞	0.989
cN+	0.221	0.099–0.554	0.001	0.244	0.091–0.651	0.005
PD/MUC	0.625	0.072–5.407	0.669
Delay after RT	0.975	0.747–1.274	0.854
CEA> 3.3 ng/mL	0.250	0.102–0.615	0.003	0.284	0.109–0.783	0.010
pre-nCRT NLR > 2.77	0.296	0.096–0.913	0.034
post-nCRT NLR > 3.23	0.372	0.160–0.864	0.021	0.365	0.145–0.918	0.032

OR, odds ratio; CI, confidence interval; RB, below peritoneal reflection; RT, radiotherapy; CEA, carcinoembryonic antigen; nCRT, neoadjuvant chemoradiation therapy; NLR, neutrophil to lymphocyte ratio.