TABLE 1.
Stability Constant (KS) and Dissociation Constant (KD) for 1 and 2 for a 1:1 Complexing between the Boronic Acid Group and D-Glucose
| Properties | Log KS | KD (mM) |
|---|---|---|
| 1 | ||
| Steady-state intensity | 1.67 (±0.03) | 21.3 (±1.1) |
| Global mean lifetime | 2.35 (±0.08) | 4.6 (±0.7) |
| Phase angle | 2.21 (±0.08) | 6.3 (±1.1) |
| Modulation | 2.29 (±0.15) | 5.4 (±1.8) |
| 2 | ||
| Steady-state intensity | 3.30 (±0.03) | 0.51 (±0.03) |
| Global mean lifetime | 4.17 (±0.06) | 0.069 (±0.009) |
| Phase angle | 3.98 (±0.03) | 0.105 (±0.008) |
| Modulation | 4.23 (±0.05) | 0.061 (±0.007) |
Note. Measured in methanol:phosphate buffer, pH 7.7 (1:3).