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. 2019 May 15;13:414. doi: 10.3389/fnins.2019.00414

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Copyright © 2019 Behensky, Katnik, Yin and Cuevas.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Afobazole fails to prevent reduced metabolic activity in neurons caused by ischemia. Bar graph of relative metabolic activity as determined with the resazurin-resorufin fluorescence assay. Values obtained for individual cultures incubated under ischemic conditions in the absence (Isch) and presence (Isch + Afob) of 100 μM afobazole are expressed as a percent of the average value obtained from cultures incubated in normal media (Control) (n = 4 for all groups). Asterisk denote significant difference from Control (p < 0.001 for both).