Figure 6.

Neural circuitry of aggression seeking and aggression severity. Top, A circuit schematic of the brain regions implicated in aggressive behavior. Bottom, The main experimental manipulations in these regions pertaining to aggressive behavior and their outcomes, summarized in a table. For the circuit diagram, the legend indicates the effect on aggressive behavior following stimulation of a region or circuit mechanism. In the table, the legend indicates experimental outcome on aggressive behavior. For this review, increased aggression seeking was operationally defined as an increased CPP score or operant responding. Increased aggression severity was operationally defined by higher number of attacks, shorter latency to attack, longer attacks, or increased intensity of an attack bout quantified by measures, such as bite number. HY, Hypothalamus; LH, lateral hypothalamus; VMH, ventromedial hypothalamus.