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. 2019 May 22;39(21):4066–4076. doi: 10.1523/JNEUROSCI.3155-18.2019

Figure 2.

Figure 2.

Bladder pressure, voided urine, and EUS-EMGs before (intact) and 7 and 28 d after incomplete SCI. DSD is fully developed at 4 weeks after injury. a, d, 40 min (2200 s) and 1 min (60 s) windows of a representative urodynamic tracing from an intact rat with bladder catheter and EUS-EMG showing filling/voiding cycles. Top, Bladder pressure. Middle, Urine secreted (weight). Bottom, External urethral sphincter EMG. Panels at base of figure, Heat plot of EMG frequency spectrogram where red represents a high power of the corresponding frequency at the current time point and blue represents low power. b, e, Spinal cord-injured rat at 1 week after injury shows a flaccid bladder with continuous flow of urine and absent sphincter activity. c, f, Typical characteristics of DSD at 4 weeks after injury. During the filling phase, there are nonvoiding contractions with increasing magnitude as well as an increase in EUS-EMG activity during voiding.