Table 4.
Diagnostic accuracy parameters for colorectal cancer detection based on quantitative faecal immunochemical test for haemoglobin threshold concentration and brand
| Brand | Threshold (µg/g faeces) | Author, year | Sensitivity1 | Specificity1 |
| Mixed cohorts | ||||
| OC-Sensor® | 25 | Rozen, 2010[17] | 60.0 (36.1-80.9) | 95.2 (94.0-96.2) |
| OC-Sensor® | 30 | Rozen, 2010[17] | 55.0 (31.5-76.9) | 95.8 (94.7-96.7) |
| OC-Sensor® | 40 | Rozen, 2010[17] | 55.0 (31.5-76.9) | 96.3 (95.3-97.2) |
| OC-Sensor® | 40 | van Turenhout, 2014[18] | 75.4 (63.5-84.9) | 94.8 (93.9-95.6) |
| OC-Sensor® | 60 | Symonds 2016[23] | 63.6 (50.9-75.1) | 91.9 (90.3-93.3) |
| OC-Sensor® | 80 | Symonds 2016[23] | 59.1 (46.3-71.0) | 93.4 (91.9-94.7) |
| HM-JACK® | 33 | Woo, 2005[19] | 50.0 (11.8-88.2) | 83.5 (73.5-90.9) |
| FOB Gold® | 10 | Auge, 2018[30] | 91.7 (71.5-98.5) | 82.2 (79.6-84.5) |
| FOB Gold® | 20 | Auge, 2018[30] | 87.5 (66.5-96.7) | 86.0 (83.6-88.1) |
| FOB Gold® | 30 | Auge, 2018[30] | 83.3 (61.8-94.5) | 89.2 (87.0-91.1) |
| FOB Gold® | 40 | Auge, 2018[30] | 83.3 (61.8-94.5) | 90.3 (88.2-92.1) |
| FOB Gold® | 50 | Auge, 2018[30] | 83.3 (61.8-94.5) | 91.4 (89.4-93.1) |
| FOB Gold® | 60 | Auge, 2018[30] | 83.3 (61.8-94.5) | 91.8 (89.9-93.5) |
| 100% Symptomatic | ||||
| HM-JACK® | 20 | Parente, 2012[24] | 61.7 (46.4-75.5) | 88.8 (84.1-92.6) |
| HM-JACKarc® | 7 | Widlak, 2017[28] | 84.0 (63.9-95.5) | 93.1 (90.2-95.4) |
1
Values are expressed as percentages and its 95% confidence interval.