Table 8.
Diagnostic accuracy parameters for significant colonic lesion detection based on quantitative faecal immunochemical test for haemoglobin threshold concentration and brand
| Brand | Threshold (µg/g faeces) | Author, year | Sensitivity1 | Specificity1 |
| Significant colonic lesion (100% symptomatic) | ||||
| OC-Sensor® | 15 | Cubiella (DC), 2014[29] | 76.2 (72.0-80.0) | 74.4 (71.7-76.9) |
| OC-Sensor® | 15 | Cubiella (VC), 2017[31] | 89.5 (84.1-93.6) | 40.6 (36.4-44.9) |
| OC-Sensor® | 20 | Cubiella (DC), 2014[29] | 74.7 (70.5-78.6) | 76.1 (73.5-78.6) |
| OC-Sensor® | 20 | Cubiella (VC), 2017[31] | 87.8 (82.2-92.2) | 42.1 (37.9-46.5) |
| HM-JACKarc® | 10 | Godber, 2016[27] | 68.9 (53.2-81.4) | 80.2 (76.1-83.7) |
| HM-JACKarc® | 15 | Godber, 2016[27] | 66.7 (50.9-79.6) | 83.1 (79.2-86.5) |
| HM-JACKarc® | 20 | Godber, 2016[27] | 64.4 (48.7-77.7) | 85.7 (81.9-88.7) |
| HM-JACKarc® | 25 | Godber, 2016[27] | 64.4 (48.7-77.7) | 87.5 (83.9-90.3) |
| HM-JACKarc® | 30 | Godber, 2016[27] | 64.4 (48.7-77.7) | 88.6 (85.2-91.4) |
| HM-JACKarc® | 35 | Godber, 2016[27] | 64.4 (48.7-77.7) | 89.2 (85.9-92.0) |
| HM-JACKarc® | 40 | Godber, 2016[27] | 64.4 (48.7-77.7) | 90.0 (86.7-92.5) |
1
Values are expressed as percentages and their 95% confidence interval. DC: Derivation cohort; VC: Validation cohort.