Fig. 6.

Documentation of an analysis using Galaxy’s history function. All actions performed within Galaxy are documented in the history frame, which contains uploaded data as well as calculated results. Original datasets are always preserved, and every subsequent analysis adds a new entry into the history frame. This screenshot illustrates how a user starts with an empty history, adds a dataset containing coordinates of human genes and SNPs, converts coordinates of genes into coordinates of promoter regions by selecting the region located 500 base pairs upstream of each gene, computes the number of SNPs per promoter, sorts the promoters by SNP density, and finally selects 100 top regions. In addition to documenting analyses, Galaxy’s history frame allows the user to share a history with colleagues