Figure 2.

Induction of the therapeutic antitumour activity. Tumour‐bearing mice were injected peritumorally or intratumorally with 100 μl total volume of 100 μg p‐c/500 μg liposome complex (□), 100 μg e‐p/500 μg liposome complex (▪), 500 μg liposome alone (▴) or PBS (◯), respectively, twice a week for 3 weeks. It was evident that, compared with control groups, p‐c treated mice showed significant tumour volume decrease and survival time prolongation both in CT26 model (A, C) and MethA fibrosarcoma model (B, D) (P < 0.05). The survival rate of the mice was 80% and 100% at day 60 for CT26 Colon carcinoma and MethA fibrosarcoma, respectively.