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. 2019 May 22;19:107. doi: 10.1186/s12906-019-2524-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — SSR attenuated renal injury and fibrosis in 5/6(A/I) model. (a) Immunoblot analysis of E-cadherin and Col-IIIexpression. (b) Western blot quantification of E-cadherin and Col-III levels.(n = 6) (c) Representative images of E-cadherin expression detected by IHC. 400 × magnification. (d) Quantitative analysis of E-cadherin positive area(n = 4) (e) Representative photomicrographs of PAS staining. 200 × magnification. (f) The severity of glomerular injury was assessed using the glomerulosclerosis (GS) score (g) Assessment of interstitial fibrosis by Masson’s trichrome staining.200 × magnification. (h) Semiquantitative result of collagen area(n = 4). Values are mean ± SD. *P < 0.05, **P < 0.01