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. 2019 May 21;19:210. doi: 10.1186/s12870-019-1809-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Putative Taxol biosynthetic pathway. The black solid arrows show the identified steps, and the red dotted arrows show the unknown steps. GGPPS: geranylgeranyl diphosphate synthase; TS: taxadiene synthase; T5αH: taxoid 5α–hydroxylase; TAT: taxadienol 5α-O-acetyl transferase; T13αH: taxoid 13α–hydroxylase; T10βH: taxoid 10β–hydroxylase; TBT: taxane-2α-O-benzoyltransferase; DBAT: 10-deacetylbaccatin III-10-O-acetyltransferase; PAM: phenylalanine aminomutase; BAPT: baccatin III-13-O-phenylpropanoyl transferase; DBTNBT: 30-N-debenzoyl-20-deoxytaxol-N-benzoyl transferase