Table 1.
Group 1 (CR yes-TF no-PDN off) N = 30 |
Group 2 (CR no-TF no/PDN on or off)N = 43 |
Group 3 (CR no-TF yes/PDN on or off) N = 66 |
P * | |
---|---|---|---|---|
Age at onset (years) | 9.5 (6.2–12.3) | 6.5 (3.3–9.8) | 6.9 (4.2–10) | 0.016 |
Disease duration (mo) | 2.6 (1.3–4.7) | 2.6 (1.3–6.4) | 3.0 (1.5–4.8) | 0.94 |
MD-global (0–10 ↑) | 7.0 (6.0–8.0) | 6.0 (5.0–7.0) | 7.0 (5.0–8.0) | 0.17 |
Parent global (0–10 ↑) | 6.0 (5.0–8.0) | 5.0 (3.5–7.0) | 5.4 (5.0–7.0) | 0.40 |
CHAQ (0–3 ↑) | 1.8 (1.1–2.6) | 1.8 (1.4–2.6) | 1.9 (1.3–2.5) | 0.94 |
DAS (0–20 ↑) | 13.0 (11.0–15.0) | 13.0 (11.0–15.0) | 13.0 (11.0–15.0) | 0.80 |
CMAS (0–52 ↓) | 16.5 (13.0–33.0) | 21.0 (14.0–35.0) | 20.7 (11.0–32.0) | 0.96 |
MMT (0–80 ↓) | 40.0 (30.0–60.0) | 47.0 (35.0–58.0) | 48.0 (34.0–56.0) | 0.84 |
CHQ PhS (40–60 ↓) | 19.8 (9.4–33.4) | 12.7 (5.2–23.5) | 14.9 (8.1–22.4) | 0.16 |
Data are medians (1st 3rdquartiles). *P: P value refers to the non-parametric Analysis of Variance (Kruskal-Wallis test); MD-global: physician’s global assessment of the patient’s overall disease activity on a 0–10-cm visual analogue scale (VAS); Parent global: parents’ global assessment of the child’s overall patient’s well-being on a 10-cm VAS; DAS Disease Activity Score; CMAS Childhood Myositis Assessment Scale, MMT manual muscle testing; CHAQ cross-culturally adapted and validated version of the Childhood Health Assessment Questionnaire); ↑ indicates that higher values correspond to a worse outcome; ↓ indicates that lower values correspond to a worse outcome