Fig. 5.

Functional analysis following SCI and treatment. Functional analysis (a) of saline-, BMMSC-, and BMMSC-IGF1-treated mice, evaluated weekly from day 1 to 28 days using the Basso Mouse Score (BMS). Body weight (b) was assessed with BMS and is represented as percent change in body weight, based on weight prior to injury (baseline). DigiGait-derived functional measurements of c gait symmetry, d stride length, e stride duration, and f stride frequency were evaluated at weeks 2, 3, and 4. Values represent mean ± SEM. *P < 0.05; **P < 0.01; and ***P < 0.001