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. 2019 May 21;10:146. doi: 10.1186/s13287-019-1223-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Lesion volume and myelination 4 weeks following SCI and treatment. Lesion volume (a) as measured by GFAP staining, which is concentrated around the lesion site, measured against total spinal cord area bilaterally from the epicenter (EC) of the injury. b Quantification of GFAP derived lesion volume. Myelination immunostaining with fluoromyelin was performed in saline (c), BMMSC (d), and BMMSC-IGF1 (e) treated SCI sections. Quantitative analysis (f) of fluoromyelin-labeled oligodendrocytes at the EC and 300 μm caudally. Bars represent means ± SEM of five mice/group. Values represent mean ± SEM. *P < 0.05 (BMMSC-IGF1: EC vs + 300), ^#P < 0.05 (+ 300: BMMSC-IGF1 vs BMMSC)