Table 9.

Lists the cardiovascular ADRs predicted by the machine learning RF and SMO models on uncharacterized drugs in SIDER

Drug name	ADR predicted by RF and SMO
DB00176 Fluvoxamine	Decompensation cardiac
DB00255 Diethylstilboestrol	Shock, cardiac failure congestive, cardiopulmonary failure, left ventricular failure, cor pulmonale, tachycardia
DB00358 Mefloquine	Tachycardia, cardiac failure congestive
DB00755 Tretinoin	Block heart, cardiac murmur, heart rate irregular, cardiac failure acute
DB00882 Clomifene	Decompensation cardiac
DB00927 Famotidine	Tachycardia, cardiac murmur, heart rate irregular, cardiac failure acute
DB01026 Ketoconazole	Tachycardia, shock, cardiac failure congestive, cardiotoxicity, cor pulmonale, left ventricular failure, heart malformation, cardiopulmonary failure
DB01394 Colchicine	Tachycardia, shock, cardiac failure congestive, cardiac murmur, cardiac disorder
DB03904 Urea	Cardiac murmur, heart rate irregular, cardiac failure acute
DB05260 Gallium nitrate	Decompensation cardiac
DB06210 Eltrombopag	Block heart, cardiac murmur, heart rate irregular, cardiac failure acute, cardiac failure, arrhythmia
DB08872 Gabapentin Enacarbil	Decompensation cardiac