Table 2.
Variable | B-NHL (n = 2535) | Control (n = 7004) | Univariate | Multivariate | ||||
---|---|---|---|---|---|---|---|---|
No. % | No. % | OR | 95% CI | P | AOR | 95% CI | P* | |
HBsAg positive | ||||||||
HBsAg-, anti-HBs-, anti-HBc- | 733 (28.9) | 2876( 41.1) | 1 | reference | 1 | reference | ||
HBsAg+, HBeAg+, anti-HBc+ | 49 (1.9) | 32 (0.5) | 6.01 | 3.82–9.45 | < 0.001 | 6.23 | 3.95–9.82 | < 0.001 |
HBsAg+, anti-HBe-, anti-HBc+ | 225 (8.9) | 208 (3.0) | 4.24 | 3.46–5.21 | < 0.001 | 4.37 | 3.55–5.37 | < 0.001 |
HBsAg+, anti-HBe+, anti-HBc+ | 139 (5.5) | 362 (5.2) | 1.51 | 1.22–1.86 | < 0.001 | 1.51 | 1.22–1.86 | < 0.001 |
HBsAg negative (A) | ||||||||
HBsAg-, anti-HBs-, anti-HBc- | 733 (28.9) | 2876 (41.1) | 1 | Reference | 1 | Reference | ||
HBsAg-, anti-HBs+, anti-HBc+ | 601 (23.7) | 1091 (15.6) | 2.16 | 1.90–2.46 | < 0.001 | 2.25 | 1.96–2.57 | < 0.001 |
HBsAg-, anti-HBs+, anti-HBc- | 460 (18.1) | 1769 (25.3) | 1.02 | 0.90–1.16 | 0.76 | 1.04 | 0.91–1.19 | 0.56 |
HBsAg-, anti-HBs-, anti-HBc+ | 309 (12.2) | 654 (9.3) | 1.85 | 1.58–2.17 | < 0.001 | 1.88 | 1.60–2.21 | < 0.001 |
HBsAg negative (B) | ||||||||
HBsAg-, anti-HBs+, anti-HBc+ | 601 (23.7) | 1091 (15.6) | 1 | Reference | 1 | Reference | ||
HBsAg-, anti-HBs-, anti-HBc- | 733 (28.9) | 2876 (41.1) | 0.46 | 0.41–0.53 | < 0.001 | 0.45 | 0.39–0.51 | < 0.001 |
HBsAg-, anti-HBs+, anti-HBc- | 139 (5.5) | 362 (5.2) | 0.47 | 0.41–0.55 | < 0.001 | 0.46 | 0.40–0.54 | < 0.001 |
HBsAg-, anti-HBs-, anti-HBc+ | 225 (8.9) | 208 (3.0) | 0.86 | 0.73–1.02 | 0.07 | 0.84 | 0.71–0.99 | 0.04 |
Abbreviations: NHL = non-Hodgkin lymphoma, OR = odds ratio, CI = confidence interval, AOR = adjusted odds ratio, HBsAg = hepatitis B surface antigen, Anti-HBs = hepatitis B surface antibody, Anti-HBc = hepatitis B core antibody. The multivariate logistic regression analyses were adjusted by age (as a continuous variable), sex and year of diagnosis. * Statistically significant at the 0.05 alpha level. A: regard HBsAg-, anti-HBs-, anti-HBc- subgroup as reference. B: regard HBsAg-, anti-HBs+, anti-HBc + subgroup as reference