Figure 7.
Levels of T cell-derived EVs in sera from patients with various inflammatory diseases. Levels of CD3+HLA-DR+ EVs (a), CD3+CD4+ EVs (b), and CD3+CD8+ EVs (c) in sera from patients with EBV infection (EBV, n = 12), atopic dermatitis (AD, n = 10), rheumatoid arthritis (RA, n = 20), and osteoarthritis (OA, n = 20) were measured by AlphaLISA and compared with those of healthy subjects (H, n = 20). The bars represent the mean ± SD∗P < 0.05, ∗∗P < 0.01, and ∗∗∗∗P < 0.0001, by the Mann–Whitney U test.