Table 6.
Combined effects of chemical contaminants and environmental factors on morphological and molecular endpoints for amphibians undergoing both natural and TH-induced metamorphosis.
| Treatment | Metamorphosis | Morphological | Molecular | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Category | Environmental | Chemical | Species | Natural | Induced | Results | Tissue | Technique | Result | References |
| Temperature | 28°C | Diuron | R. catesbeiana | Y | Liver | qPCR | ↑thibz | (195) | ||
| 34°C | R. catesbeiana | Y | Liver | qPCR | ↑dio2, klf9 | (195) | ||||
| 5°C | Ibuprofen | R. catesbeiana | T3 | C-skin | qPCR | ↑klf9 | (65) | |||
| 5°C | Triclosan | R. catesbeiana | T3 | C-skin | qPCR | ↑klf9 | (65) | |||
| 5°C to 24°C | R. catesbeiana | T3 | C-fin | qPCR | ↑thrb | (65) | ||||
| UVBR | UVBR | 4-Tert-octylphenol | R. pipiens | Y | ↓ metamorphic rate | Tail | qPCR | ↑thrb | (236) | |