Table 4.
Multiple linear regression models of refraction and ocular biometry by height, weight and BMI
| Model 1 | P value | Model 2 | P value | Model 3 | P value | |
| Height (per 10 cm) | ||||||
| SER (D) | −0.59 (−0.70 to –0.49)* | <0.01 | −0.26 (−0.45 to –0.08) | <0.01 | −0.21 (−0.40 to –0.01) | <0.05 |
| AL (mm) | 0.40 (0.34 to 0.47) | <0.01 | 0.18 (0.07 to 0.29) | <0.01 | 0.14 (0.03 to 0.26) | <0.05 |
| CCT (μm) | 4.03 (1.97 to 6.08) | <0.01 | 2.43 (−1.29 to 6.16) | 0.20 | 3.41 (−0.76 to 7.58) | 0.11 |
| ACD (mm) | 0.05 (0.04 to 0.07) | <0.01 | 0.02 (−0.01 to 0.05) | 0.17 | 0.02 (−0.02 to 0.05) | 0.34 |
| LT (mm) | −0.04 (−0.05 to –0.02) | <0.01 | −0.01 (−0.03 to 0.02) | 0.57 | −0.01 (−0.03 to 0.02) | 0.75 |
| VCD (mm) | 0.38 (0.32 to 0.44) | <0.01 | 0.17 (0.06 to 0.27) | <0.01 | 0.13 (0.02 to 0.25) | <0.05 |
| CC (mm) | 0.01 (−0.01 to 0.03) | 0.13 | 0.01 (−0.02 to 0.04) | 0.41 | 0.01 (−0.03 to 0.04) | 0.81 |
| AL/CC ratio | 0.05 (0.04 to 0.06) | <0.01 | 0.02 (0.01 to 0.03) | <0.01 | 0.02 (0.01 to 0.03) | <0.05 |
| Weight (per 10 kg) | ||||||
| SER (D) | −0.65 (−0.79 to –0.51) | <0.01 | −0.21 (−0.39 to −0.03) | <0.05 | −0.18 (−0.36 to 0.01) | 0.07 |
| AL (mm) | 0.46 (0.38 to 0.55) | <0.01 | 0.16 (0.05 to 0.26) | <0.01 | 0.15 (0.04 to 0.26) | <0.01 |
| CCT (μm) | 5.56 (2.93 to 8.20) | <0.01 | 3.68 (0.06 to 7.29) | <0.05 | 4.44 (0.42 to 8.47) | <0.05 |
| ACD (mm) | 0.05 (0.03 to 0.07) | <0.01 | −0.01 (−0.03 to 0.02) | 0.90 | −0.01 (−0.03 to 0.03) | 0.87 |
| LT (mm) | −0.04 (−0.05 to –0.02) | <0.01 | 0.01 (−0.02 to 0.02) | 0.95 | 0.01 (−0.02 to 0.03) | 0.96 |
| VCD (mm) | 0.44 (0.36 to 0.53) | <0.01 | 0.16 (0.06 to 0.27) | <0.01 | 0.15 (0.04 to 0.26) | <0.01 |
| CC (mm) | 0.03 (0.01 to 0.05) | <0.05 | 0.02 (−0.01 to 0.05) | 0.11 | 0.02 (−0.01 to 0.05) | 0.14 |
| AL/CC ratio | 0.05 (0.04 to 0.06) | <0.01 | 0.01 (−0.01 to 0.02) | 0.10 | 0.01 (−0.01 to 0.02) | 0.16 |
| BMI (per 10 kg/m2) | ||||||
| SER (D) | −0.64 (−1.15 to −0.13) | <0.05 | −0.26 (−0.73 to 0.20) | 0.26 | −0.27 (−0.74 to 0.20) | 0.25 |
| AL (mm) | 0.53 (0.21 to 0.84) | <0.01 | 0.20 (−0.07 to 0.47) | 0.15 | 0.23 (−0.05 to 0.50) | 0.10 |
| CCT (μm) | 9.50 (0.35 to 18.65) | <0.05 | 6.37 (−2.79 to 15.53) | 0.17 | 7.19 (−2.87 to 17.25) | 0.16 |
| ACD (mm) | 0.03 (−0.05 to 0.10) | 0.50 | −0.03 (−0.10 to 0.04) | 0.46 | −0.02 (−0.10 to 0.05) | 0.52 |
| LT (mm) | −0.02 (−0.08 to 0.03) | 0.42 | 0.01 (−0.05 to 0.07) | 0.79 | 0.01 (−0.06 to 0.07) | 0.86 |
| VCD (mm) | 0.55 (0.24 to 0.85) | <0.01 | 0.23 (−0.03 to 0.50) | 0.09 | 0.25 (−0.03 to 0.52) | 0.08 |
| CC (mm) | 0.06 (−0.01 to 0.14) | 0.09 | 0.04 (−0.03 to 0.11) | 0.25 | 0.06 (−0.02 to 0.14) | 0.13 |
| AL/CC ratio | 0.04 (0.01 to 0.08) | <0.05 | 0.01 (−0.02 to 0.04) | 0.58 | 0.01 (−0.03 to 0.04) | 0.67 |
Model 1 constructs based on crude data. In the next two models, we controlled, in turn, for age and gender or for age, gender, parental myopia, family income, reading and writing distance and time spent outdoors.
*Each value represents a separate regression model, with height, weight or BMI used as the independent variable, the refraction or individual ocular biometrics used as the dependent variable, either alone or with various confounders. Data in parentheses represent the 95% CI.
ACD, anterior chamber depth; AL, axial length; BMI, body mass index; CC, corneal curvature; CCT, central corneal thickness; LT, lens thickness; SER, spherical equivalent refraction; VCD, vitreous chamber depth.