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. 2019 May 8;10:431. doi: 10.3389/fgene.2019.00431

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Copyright © 2019 Sheng, Wang, Xu, Shan and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of the RNA expression profile in HCC. (A–D) volcano plots (left) display differentially expressed transcripts, and the hierarchical cluster analyses on the right of each panel display differential expression of RNAs in four HCC tumor tissues and their controls. (A) mRNAs, (B) lncRNAs, (C) miRNAs, and (D) circRNA. Green and red dots represent downregulated and upregulated RNAs respectively in tumor tissues compared with adjacent tissues. Black dots indicate no significant difference.