Table 1.
LECs and PECs have similar but distinct transcriptional profiles.
| Gene | avg_log2(LEC/PEC) | pct.LEC | pct.PEC | pval | Pval adj |
|---|---|---|---|---|---|
| CCL21 | 5.158128464 | 0.763 | 0.045 | 2.00E-11 | 2.26E-07 |
| TFF3 | 3.305995867 | 0.789 | 0.045 | 1.17E-11 | 1.33E-07 |
| NTS | 2.140331515 | 0.316 | 0 | 6.73E-05 | 0.760564313 |
| ADIRF | 1.637091524 | 0.711 | 0.227 | 2.39E-06 | 0.027008311 |
| S100A10 | 1.47389027 | 0.763 | 0.386 | 4.70E-06 | 0.053149996 |
| S100A6 | 1.29723903 | 0.789 | 0.318 | 1.39E-06 | 0.015742032 |
| FABP4 | 1.086755403 | 0.658 | 0.091 | 2.56E-07 | 0.002893748 |
| JUNB | −1.508928712 | 0.158 | 0.636 | 7.56E-06 | 0.085490214 |
| AC090498.1 | −1.65001069 | 0.184 | 0.545 | 1.62E-04 | 1 |
| ZFP36 | −1.665549178 | 0.079 | 0.5 | 6.20E-05 | 0.700906334 |
| NBEAL1 | −1.699311818 | 0.105 | 0.455 | 2.87E-04 | 1 |
| RDX | −1.836136132 | 0.053 | 0.409 | 1.89E-04 | 1 |
| C11orf96 | −1.881095457 | 0 | 0.273 | 5.79E-04 | 1 |
| FCN3 | −1.963822515 | 0.026 | 0.477 | 1.15E-05 | 0.129553478 |
| SAT1 | −2.283288374 | 0.026 | 0.5 | 3.07E-06 | 0.034715003 |
| MTRNR2L12 | −2.322539602 | 0.053 | 0.523 | 6.06E-06 | 0.068538598 |
| PLPP3 | −2.351071763 | 0 | 0.318 | 1.66E-04 | 1 |
| HSPG2 | −2.394084071 | 0.026 | 0.477 | 5.88E-06 | 0.066463691 |
| CCL14 | −2.467042053 | 0.053 | 0.477 | 1.60E-05 | 0.181344818 |
| IFI27 | −2.604129481 | 0.079 | 0.659 | 5.81E-08 | 6.57E-04 |
| BST2 | −2.622236874 | 0 | 0.432 | 5.77E-06 | 0.065268266 |
| RNASE1 | −2.767317205 | 0 | 0.523 | 2.99E-07 | 0.003384829 |
Shown is the average log2 gene expression fold change between LEC and PEC in non-diseased livers, the percent of cells in each subset that expresses a given gene, and the raw and adjusted P-values. Data was filtered to include only genes in which the p-value between LEC and PEC was < 0.0006.