Table 1.
Participant baseline characteristics
| Baseline characteristics | N=14 |
| Mean age (SD), years | 35.5 (17.1) |
| Sex, female:male | 7:7 |
| Mean FEV1, L (SD) | 1.75 (0.90) |
| Mean FEV1, % predicted (SD) | 48.9 (20.1) |
| Mean FVC, L (SD) | 2.88 (1.15) |
| Mean FVC, % predicted (SD) | 68.4 (18.4) |
| Genotype, n (%) | |
| Homozygous F508del F508del + another mutation 2 other mutations |
7 (50) 6 (43) 1 (7) |
| Main usual airway clearance technique, n (%) | |
| Positive expiratory pressure Autogenic drainage Oscillatory device (flutter/acapella) Active cycle of breathing techniques |
6 (43) 5 (36) 2 (14) 1 (7) |
| Mucoactive agents, n (%)* | |
| DNase Hypertonic saline Mannitol |
13 (93) 4 (29) 4 (29) |
*Some participants were taking more than one mucoactive agent.
FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.