. Author manuscript; available in PMC: 2019 May 22.

Published in final edited form as: J Urol. 2017 Dec 26;199(6):1510–1517. doi: 10.1016/j.juro.2017.12.048

Table 2.

Standardized incidence ratio stratified by age in consecutive years and compared to 2004

	All Ages 50 or Greater		Ages 50–74		Ages 75 or Greater
Metastasis	Yr to Yr	2004	Yr to Yr	2004	Yr to Yr	2004

None:
2005	0.93 (0.92–0.94)^*	0.93 (0.92–0.94)^*	0.93 (0.92–0.95)^*	0.93 (0.92–0.95)^*	0.93 (0.90–0.95)^*	0.93 (0.90–0.95)^*
2006	1.09 (1.07–1.10)^*	1.01 (1.00–1.02)^†	1.11 (1.09–1.12)^*	1.03 (1.02–1.05)^*	1.04 (1.02–1.07)^*	0.97 (0.94–0.99)^*
2007	1.03 (1.02–1.05)^*	1.05 (1.04–1.06)^*	1.05 (1.03–1.06)^*	1.08 (1.07–1.10)^*	1.00 (0.97–1.03)	0.97 (0.94–0.99)^†
2008	0.91 (0.90–0.92)^*	0.95 (0.94–0.96)^*	0.92 (0.91–0.94)^*	1.00 (0.98–1.01)	0.87 (0.84–0.89)^*	0.84 (0.82–0.86)^*
2009	0.97 (0.96–0.98)^*	0.92 (0.91–0.93)^*	0.99 (0.98–1.00)	0.99 (0.98–1.00)	0.91 (0.89–0.94)^*	0.77 (0.74–0.79)^*
2010	0.95 (0.94–0.96)^*	0.87 (0.86–0.88)^*	0.95 (0.93–0.96)^*	0.94 (0.92–0.95)^*	0.95 (0.92–0.98)^*	0.73 (0.71–0.75)^*
2011	0.99 (0.97–1.00)^†	0.86 (0.85–0.87)^*	0.99 (0.98–1.00)	0.93 (0.91–0.94)^*	0.97 (0.94–1.00)^†	0.71 (0.69–0.73)^*
2012	0.80 (0.79–0.81)^*	0.69 (0.68–0.70)^*	0.82 (0.80–0.83)^*	0.76 (0.75–0.77)^*	0.76 (0.74–0.79)^*	0.54 (0.52–0.56)^*
2013	0.93 (0.92–0.95)^*	0.65 (0.64–0.65)^*	0.93 (0.92–0.95)^*	0.71 (0.70–0.72)^*	0.93 (0.90–0.97)^*	0.50 (0.49–0.52)^*
2014	0.89 (0.87–0.90)^*	0.57 (0.56–0.58)^*	0.88 (0.87–0.90)^*	0.62 (0.61–0.63)^*	0.90 (0.86–0.93)^*	0.45 (0.44–0.47)^*
Pelvic lymph node:
2005	0.98 (0.88–1.09)	0.98 (0.88–1.09)	0.99 (0.88–1.11)	0.99 (0.88–1.11)	0.91 (0.62–1.34)	0.91 (0.62–1.34)
2006	1.01 (0.91–1.13)	0.99 (0.89–1.10)	1.00 (0.89–1.12)	0.99 (0.88–1.11)	1.11 (0.76–1.64)	1.01 (0.69–1.48)
2007	1.15 (1.04–1.28)^*	1.14 (1.03–1.27)^†	1.11 (1.00–1.25)	1.10 (0.98–1.23)	1.40 (0.99–1.99)	1.42 (0.99–2.02)
2008	0.98 (0.88–1.08)	1.11 (1.00–1.24)^†	0.95 (0.85–1.07)	1.05 (0.93–1.18)	1.10 (0.80–1.51)	1.56 (1.10–2.21)^†
2009	1.01 (0.91–1.12)	1.12 (1.01–1.25)^†	1.02 (0.91–1.14)	1.07 (0.95–1.20)	0.95 (0.70–1.30)	1.49 (1.05–2.11)^†
2010	1.09 (0.99–1.21)	1.23 (1.11–1.36)^*	1.08 (0.97–1.21)	1.16 (1.04–1.29)^†	1.15 (0.84–1.56)	1.70 (1.21–2.40)^*
2011	0.98 (0.89–1.08)	1.21 (1.09–1.34)^*	0.94 (0.85–1.05)	1.09 (0.98–1.23)	1.15 (0.86–1.52)	1.95 (1.40–2.72)^*
2012	1.00 (0.91–1.10)	1.21 (1.09–1.34)^*	1.02 (0.92–1.14)	1.12 (1.00–1.25)	0.91 (0.69–1.21)	1.78 (1.27–2.50)^*
2013	1.09 (0.99–1.20)	1.31 (1.18–1.45)^*	1.07 (0.96–1.19)	1.20 (1.07–1.34)^*	1.18 (0.89–1.56)	2.10 (1.51–2.92)^*
2014	1.12 (1.02–1.23)^†	1.47 (1.33–1.62)^*	1.12 (1.01–1.24)^†	1.34 (1.20–1.49)^*	1.12 (0.87–1.46)	2.36 (1.71–3.26)^*
Distant:
2005	0.98 (0.93–1.04)	0.98 (0.93–1.04)	1.05 (0.97–1.13)	1.05 (0.97–1.13)	0.93 (0.85–1.02)	0.93 (0.85–1.02)
2006	0.97 (0.92–1.03)	0.96 (0.91–1.01)	0.95 (0.88–1.02)	0.99 (0.91–1.07)	1.00 (0.91–1.10)	0.93 (0.85–1.03)
2007	0.98 (0.93–1.04)	0.94 (0.89–1.00)^†	0.96 (0.89–1.04)	0.95 (0.88–1.03)	1.00 (0.91–1.10)	0.94 (0.85–1.03)
2008	0.97 (0.92–1.02)	0.91 (0.87–0.97)^*	1.01 (0.93–1.09)	0.96 (0.89–1.04)	0.93 (0.85–1.03)	0.87 (0.79–0.96)^*
2009	0.99 (0.93–1.04)	0.90 (0.85–0.95)^*	1.03 (0.95–1.11)	0.99 (0.91–1.07)	0.95 (0.85–1.05)	0.83 (0.75–0.91)^*
2010	1.02 (0.96–1.07)	0.92 (0.87–0.97)^*	1.02 (0.95–1.10)	1.01 (0.93–1.09)	1.01 (0.91–1.12)	0.84 (0.76–0.92)^*
2011	1.00 (0.94–1.05)	0.91 (0.87–0.96)^*	1.02 (0.94–1.10)	1.03 (0.95–1.11)	0.97 (0.88–1.08)	0.81 (0.74–0.90)^*
2012	1.07 (1.01–1.13)^†	0.97 (0.92–1.03)	1.01 (0.94–1.09)	1.04 (0.96–1.12)	1.13 (1.02–1.24)^†	0.91 (0.83–1.01)
2013	1.05 (0.99–1.10)	1.02 (0.97–1.07)	1.05 (0.97–1.13)	1.09 (1.01–1.18)^†	1.05 (0.95–1.15)	0.96 (0.87–1.05)
2014	1.02 (0.97–1.07)	1.04 (0.99–1.10)	1.06 (0.99–1.14)	1.16 (1.07–1.25)^*	0.98 (0.89–1.08)	0.93 (0.85–1.03)

p <0.01.

^†

p <0.05.