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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2018 Aug 8;1865(7):1865–1875. doi: 10.1016/j.bbadis.2018.08.011

Fig. 5:

Fig. 5:

Myocardial morphology and ultrastructure in 4- and 12 month-old WT and Akt2-AMPKα2 double knockout (DKO) mice. A: Representative FITC-conjugated lectin staining depicting the transverse sections of left ventricular myocardium (×400); B: Representative Masson trichrome staining depicting fibrosis formation; C: Mitochondria and sarcomere ultrastructure using transmission electron microscopy. D: Quantitative analysis of cardiomyocyte cross-sectional area; and E: Quantitative analysis of fibrotic area (Masson’s trichrome-stained area in light blue color normalized to the total myocardial area). Mean ± SEM, n = 9–12 mice per group. *p < 0.05 vs. WT-4 month-old group, # p < 0.05 vs. WT-12 month-old group.